Breast cancer chemo resistance



Cell Stem Cell ; 1: J Mol Histo ; Breast tumors containing breast cancer chemo resistance cancer stem cells have increased resistance to chemo- and radiotherapy, a higher relapse rate and increased susceptibility to metastasis. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. The cancer stem cell:



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Breast cancer chemo resistance
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Transcription of Notch genes is activated. The extrinsic group includes all microenvironment influences such as hypoxia or epithelial-mesenchymal transitions EMT that lead to chemoresistance [27]. Stem Cell Rev Rep ; 7: CXCR4 is a receptor for stromal cell-derived factor 1 SDF1 which plays a critical role in cell migration and has been associated with tumor metastasis due to its metastatic potential. Tumor dormancy and cancer stem cells:

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Cell stem cell ; 4: Cross talk between hedgehog and epithelial-mesenchymal transition path-ways in gastric pit cells and in diffuse-type gastric cancers. Karamboulas C, Ailles L. Controversies in Cancer Stem Cells: Acta Pharmaceutica Sinica B ; 3:

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